于菲菲，博士，教授，博士生导师，中国农业大学杰出人才，国家优秀青年科学基金获得者，国家重点研发项目首席科学家。主要从事高粱等粮饲作物耐盐碱胁迫应答及饲草品质调控机理的研究。在Science、Science Advances、Nature Plants、Trends in Plant Science、National Science Review、The Plant Cell、Molecular Plant等领域内代表性期刊发表SCI论文30余篇，授权/申请专利5项，参编著作3部。相关研究成果入选2023年“央视国内/国际十大科技新闻进展”和两院院士评选“2023年中国/世界十大科技进展新闻”。

学习经历

2012—2016：中国科学院遗传与发育生物学研究所，博士

2009—2012：山东农业大学，生命科学学院，硕士

2005—2009：曲阜师范大学，生命科学学院，学士

工作经历

2022—：中国农业大学，草业科学与技术学院，教授

2017—2021：中国科学院遗传与发育生物学研究所，助理研究员，副研究员

近五年部分论文发表情况：

(#These authors contributed equally to this work; *Corresponding author)

1.  Yu F.*, and Xie. Q. (2023). ER-associated ubiquitin-conjugating enzyme: a key regulator of grain yield and stress resistance in crops. Trends in Plant Science S1360-1385(23):384-389. (IF=13.479)

2.  Zhang H.#, Yu F.#,*, Xie P.#, Sun S.#, Qiao X.#, Tang S., Chen C., Yang S., Mei C., Yang D., et al. (2023). A Gγ protein regulates alkaline sensitivity in crops. Science 379:eade8416. (IF=63.714)

3.    Sun W.#, Zhang H.#, Yang S.#, Liu L.#, Xie P., Li J., Zhu Y., ... Xie Q.*, Zhang H.*, Yu F.*(2023). Genetic modification of Gγ subunit AT1 enhances salt-alkali tolerance in main graminaceous crops. National Science Review  10(6):nwad075. （IF=23.178)

4.    Yu F*, Liu C, Zhang H, Xie Q.* (2023). A G protein γ subunit participates in crop alkaline sensitivity by modulating H2O2 transporter PIP2s.Journal of Molecular Cell Biology15(3):mjad020. (IF=8.185)

5.    Liu G., Liang J., Lou L., Tian M., Zhang X., Liu L., Zhao Q., Xia R., Wu Y., Xie Q.*, and YuF.*(2022). The deubiquitinases UBP12 and UBP13 integrate with the E3 ubiquitin ligase XBAT35.2 to modulate VPS23A stability in ABA signaling. Science Advances 8(14):eabl5765. (IF=14.136)

6.       Zhang D.#, Tang S.#, Xie P., Yang D., Wu Y., Cheng S., Xin P., Chu J., Yu F.* and Xie Q.* (2022). Creation of fragrant sorghum by CRISPR/Cas9. Journal of Integrative Plant Biology 64(5):961-96 (IF=7.061)

7.       Xie P., Tang S., Chen C., Zhang H., Yu F., Li C., Wei H., Sui Y., Wu C., Diao X., Wu Y.*, and Xie Q.* (2022) Natural variation in Glume Coverage 1 causes naked grains in sorghum. Nature Communications 13(1):1068.

8.    Chen Q., Wu Y., Yu F., and Xie Q. (2022). Coordinative regulation of ERAD and selective autophagy in plants. Essays in Biochemistry 66(2):179-188. (IF=7.258)

9.       Song Z., Chen X., Luo L., Yu F., Liu J., and Han J. (2022). UBA domain protein SUF1 interacts with NatA-complex subunit NAA15 to regulate thermotolerance in Arabidopsis. Journal of Integrative Plant Biology64(7):1297-1302. (IF=7.061)

10.    Chen C., Shang X., Sun M., Tang S., Khan A., Zhang D., Yan H., Jiang Y., Yu F., Wu Y. and Xie Q.*(2022) Comparative transcriptome analysis of two sweet sorghum genotypes with different salt tolerance abilities to reveal the mechanism of salt tolerance.International Journal of Molecular Science 23:2272. (IF=6.208)

11. Hao D., Jin L., Wen X., Yu F., Xie Q., and Guo H. (2021). The RING E3 ligase SDIR1 destabilizes EBF1/EBF2 and modulates the ethylene response to ambient temperature fluctuations in Arabidopsis. Proceedings of the National Academy of Sciences of the U. S.A 118(6):e2024592118. (IF=11.205) 

12. Chen Q., Liu R., Wu Y., Wei S., Wang Q., Zheng Y., Xia R., Shang X., Yu F., Yang X., et al. (2021). ERAD-related E2 and E3 enzymes modulate the drought response by regulating the stability of PIP2 aquaporins. The Plant Cell 33(8):2883-2898.(IF=12.085)

13.Yu F.#,*, Cao X.#, Liu G., Wang Q., Xia R., Zhang X., and Xie Q.* (2020). ESCRT-I Component VPS23A is targeted by E3 ubiquitin ligase XBAT35 for proteasome-mediated degradation in modulating ABA signaling. Molecular Plant 13(11):1556-1569. (IF=13.164)   2020 Sep 9.

14. Lou L.#, Yu F.#,*, TianM., Liu G.,  Wu Y., Wu Y., XiaR., PardoJ., Guo Y. and Xie Q.*(2020). ESCRT-I component VPS23A sustains salt tolerance by strengthening the SOS module in Arabidopsis. Molecular Plant 13(8):1134-1148. (IF=13.164)  2020 May 18

15. Chen Q., Yu F.* and Xie Q.* (2020). Insights into endoplasmic reticulum-associated degradation in plants. New Phytologist 226(2):345-350. (IF=8.795)

16. Wang Q., Yu F.* and Xie Q.* (2020). Balancing growth and adaptation to stress: Crosstalk between brassinosteroid and abscisic acid signaling. Plant Cell & Environment 43(10):2325-2335. (IF=7.044) 2020 Aug 31

17.Zhang H., Xie P., Xu X., Xie Q.* and Yu F.* (2020). Heterotrimeric G protein signalling in plant biotic and abiotic stress response. Plant Biology23(S1):20-30. (IF=2.371)

18. Yu F. and Xie Q.* (2017). Non-26S proteasome endomembrane trafficking pathways in ABA signaling. Trends in Plant Science 22:976-985. (IF=13.479)

19. Yu F., Lou L., Tian M., Li Q., Ding Y., Wu Y., Yang S. and Xie Q.* (2016). ESCRT-I component VPS23A modulates ABA signaling by recognizing K63-linked ubiquitin of ABA receptors for endosomal degradation. Molecular Plant 9:1570-1582. (IF=10.812)

20. Yu F. #, Wu Y.# and Xie Q.* (2016). Ubiquitin-proteasome system in ABA signaling: from perception to action. Molecular Plant 9:21-33. (IF=10.812)

21. Yu F., Wu Y. and Xie Q.* (2015). Precise protein post-translational modifications modulate ABI5 activity. Trends in Plant Science 20:569-575. (IF=14.006)

22. ZhangC., Wei Y., Xu L., Wu K., Yang L., Shi C., Yang G., Chen D., YuF., Xie Q., Ding S., Wu J.*(2020). A bunyavirus-inducible ubiquitin ligase targets RNA polymerase IV for degradation during viral pathogenesis in rice. Molecular Plant 13:836-850. (IF=13.164)

23.Han J., Yang X., Wang Q., Tang L., Yu F., Huang X., Wang Y., Liu J. and Xie Q.* (2019). The β5 subunit is essential for intact 26S proteasome assembly to specifically promote plant autotrophic growth under salt stress. New Phytologist 221:1359-1368. (IF=7.299)

24. Hu B., Jiang Z., Wang W., Qiu Y., Zhang Z., Liu Y., Li A., Gao X., Liu L., Qian Y., Huang X., Yu F., Kang S., Wang Y., Xie J., Cao S., Zhang L., Wang Y., Xie Q., Kopriva S. and Chu C.* (2019). Nitrate-NRT1.1B-SPX4 cascade integrates nitrogen and phosphorus signalling networks in plants. Nature Plants 5:401-413. (IF=14.576)

Researchgate: https://www.researchgate.net/profile/Feifei-Yu-3

参编书籍：

[1] 于菲菲，谢旗，赵庆臻，刘利静. 2020.《泛素家族介导的蛋白质降解和细胞自噬：第十章植物蛋白质的泛素化修饰》, 邱小波等主编, 科学出版社

[2] Yu F. and Xie Q. (2019) Phytochromes: Chapter 6 Approaches to identify protein ubiquitination sites in plants. Springer, DOI: 10.1007/978-1-4939-9612-4. (Book chapter)

[3] Wu Y., Yu F. and Xie Q. (2014) Abscisic acid: metabolism, transport and signaling: Chapter 9 Protein ubiquitination and sumoylation in ABA signaling. Springer, DOI: 1007/978-94-017-9424-4. (Book chapter)

专利：

[1] ZL 202111157797.2，谢旗于菲菲张会丽，高粱耐盐碱相关基因AT1及其在作物耐盐碱方面的应用。[2] ZL201610973639.7，谢旗于菲菲，植物耐旱相关蛋白VPS23A及其编码基因与应用。